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HONEY AGAINST ONCOLOGY

HONEY AGAINST ONCOLOGY

Cancer cells are characterized by insufficient apoptotic turnover and uncontrolled proliferation of body tissues. The chemicals used for treatment are apoptosis inducers.

Modern research suggests that honey may have anti-tumor effects through several mechanisms. Honey has anti-tumor effects through its interactions with several cellular signaling pathways, including the induction of apoptosis, antimutagenic, antiproliferative and anti-inflammatory pathways.

Honey mediates apoptosis in many types of cancer cells by depolarizing the mitochondrial membrane. It increases the activation of caspase 3 and the degradation of ADP-ribose in human colon cancer cells, which is associated with its high phenolic component. In addition, honey contributes to the control of cell breakdown by modulating the expression of PRO and anti-apoptotic proteins in colon cancer. Honey promotes the expression of p53, caspase 3, and the pro-apoptotic protein BAC, and at the same time reduces the expression of the Bc12 protein, which disrupts the process of cell decay and death. Honey is used orally, and various mechanisms to contain the disease are involved.

Apoptosis was produced by manuka honey, which includes PARP activation, DNA fragmentation, and loss of Bcl-2 expression.

Honey alters the body’s immune responses. Honey has been shown to prevent uncontrolled cell division, induce apoptosis, alter cell cycle progression, and cause mitochondrial membrane depolarization in several cancers. Among them, such as skin cancer (melanoma), adenocarcinoma, cervical, liver, prostate cancer, renal cell carcinoma, bladder cancer, lung cancer, leukemia, osteosarcoma and oral squamous cell carcinoma. In addition, honey can inhibit the spread of several forms of tumor when simulated in animals, including breast cancer, carcinoma, melanoma, colon cancer, liver cancer and bladder cancer.

There is currently no universal cure for cancer. And, of course, more research is required in order to improve our understanding of the positive impact of a particular remedy in this matter. But do not forget that most of the drugs used for chemotherapy are inducers of cellular decay. Therefore, it is the apoptotic properties of honey that make it a possible natural analogue of anti-cancer agents.

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